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A Carboxy-Terminal Trimerization Domain Stabilizes Conformational Epitopes on the Stalk Domain of Soluble Recombinant Hemagglutinin Substrates

Recently, a new class of broadly neutralizing anti-influenza virus antibodies that target the stalk domain of the viral hemagglutinin was discovered. As such, induction, isolation, characterization, and quantification of these novel antibodies has become an area of intense research and great interes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Krammer, Florian, Margine, Irina, Tan, Gene S., Pica, Natalie, Krause, Jens C., Palese, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426533/
https://ncbi.nlm.nih.gov/pubmed/22928001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043603
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