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Gene interaction enrichment and network analysis to identify dysregulated pathways and their interactions in complex diseases

BACKGROUND: The molecular behavior of biological systems can be described in terms of three fundamental components: (i) the physical entities, (ii) the interactions among these entities, and (iii) the dynamics of these entities and interactions. The mechanisms that drive complex disease can be produ...

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Bibliographic Details
Main Authors: Liu, Yu, Koyutürk, Mehmet, Barnholtz-Sloan, Jill S, Chance, Mark R
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426489/
https://ncbi.nlm.nih.gov/pubmed/22694839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-65
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