Genetic locus on mouse chromosome 7 controls elevated heart rate

Elevated heart rate (HR) is a risk factor for cardiovascular diseases. The goal of the study was to map HR trait in mice using quantitative trait locus (QTL) analysis followed by genome-wide association (GWA) analysis. The first approach provides mapping power and the second increases genome resolut...

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Bibliographic Details
Main Authors: Smolock, Elaine M., Ilyushkina, Irina A., Ghazalpour, Anatole, Gerloff, Janice, Murashev, Arkady N., Lusis, Aldons J., Korshunov, Vyacheslav A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426427/
https://ncbi.nlm.nih.gov/pubmed/22589454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00041.2012
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