Nonsynonymous variants in mt-Nd2, mt-Nd4, and mt-Nd5 are linked to effects on oxidative phosphorylation and insulin sensitivity in rat conplastic strains

Common inbred strains of the laboratory rat can be divided into four different mitochondrial DNA haplotype groups represented by the SHR, BN, LEW, and F344 strains. In the current study, we investigated the metabolic and hemodynamic effects of the SHR vs. LEW mitochondrial genomes by comparing the S...

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Autors principals: Houštěk, Josef, Hejzlarová, Kateřina, Vrbacký, Marek, Drahota, Zdeněk, Landa, Vladimír, Zídek, Václav, Mlejnek, Petr, Šimáková, Miroslava, Šilhavý, Jan, Mikšík, Ivan, Kazdová, Ludmila, Oliyarnyk, Olena, Kurtz, Theodore, Pravenec, Michal
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426424/
https://ncbi.nlm.nih.gov/pubmed/22414913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00156.2011
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