A hypermorphic SP1-binding CD24 variant associates with risk and progression of multiple sclerosis

A large number of risk alleles have been identified for multiple sclerosis (MS). However, how genetic variations may affect pathogenesis remains largely unknown for most risk alleles. Through direct sequencing of CD24 promoter region, we identified a cluster of 7 new single nucleotide polymorphisms...

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Autori principali: Wang, Lizhong, Liu, Runhua, Li, Dongling, Lin, Shili, Fang, Xianfeng, Backer, Grant, Kain, Mandy, Rammoham, Kottil, Zheng, Pan, Liu, Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426393/
https://ncbi.nlm.nih.gov/pubmed/22937211
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