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Single nucleotide polymorphisms of the adult intestinal stem cell marker Lgr5 in primary and metastatic colorectal cancer

Morphological and clinical heterogeneity of advanced colorectal cancer is probably caused by genetic variability in putative cancer stem cell genes, including Lgr5. Here, we investigated 23 variants of the Lgr5 gene in normal tissue, primary tumors, lymph node metastases and distant metastases of st...

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書誌詳細
主要な著者: Kleist, Britta, Xu, Li, Kersten, Christian, Seel, Violetta, Li, Guojun, Poetsch, Micaela
フォーマット: Artigo
言語:Inglês
出版事項: e-Century Publishing Corporation 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426388/
https://ncbi.nlm.nih.gov/pubmed/22937206
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