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T(H)17 Differentiation is the Default Program for DPP2-deficient T cell Differentiation

DPP2 (dipeptidyl peptidase 2) is an N-terminal dipeptidase, required for maintaining lymphocytes in a resting state. Mutant mice with T cell-specific knock-down (kd) of DPP2 (lck-DPP2 kd) were generated and analyzed for their phenotype. Normal thymocyte development and a modest increase in the propo...

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Detalhes bibliográficos
Main Authors: Mele, Deanna A., Sampson, James F., Huber, Brigitte T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426301/
https://ncbi.nlm.nih.gov/pubmed/21469121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041157
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