Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes

Protein synthesis and autophagic degradation are regulated in an opposite manner by mammalian target of rapamycin (mTOR), whereas under certain conditions it would be beneficial if they occured in unison to handle rapid protein turnover. We observed a distinct cellular compartment at the trans-side...

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Autors principals: Narita, Masako, Young, Andrew R.J., Arakawa, Satoko, Samarajiwa, Shamith A., Nakashima, Takayuki, Yoshida, Sei, Hong, Sungki, Berry, Lorraine S., Reichelt, Stefanie, Ferreira, Manuela, Tavaré, Simon, Inoki, Ken, Shimizu, Shigeomi, Narita, Masashi
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426290/
https://ncbi.nlm.nih.gov/pubmed/21512002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1205407
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