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Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes
Protein synthesis and autophagic degradation are regulated in an opposite manner by mammalian target of rapamycin (mTOR), whereas under certain conditions it would be beneficial if they occured in unison to handle rapid protein turnover. We observed a distinct cellular compartment at the trans-side...
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Glavni autori: | , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2011
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3426290/ https://ncbi.nlm.nih.gov/pubmed/21512002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1205407 |
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