Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes

Protein synthesis and autophagic degradation are regulated in an opposite manner by mammalian target of rapamycin (mTOR), whereas under certain conditions it would be beneficial if they occured in unison to handle rapid protein turnover. We observed a distinct cellular compartment at the trans-side...

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Detalhes bibliográficos
Main Authors: Narita, Masako, Young, Andrew R.J., Arakawa, Satoko, Samarajiwa, Shamith A., Nakashima, Takayuki, Yoshida, Sei, Hong, Sungki, Berry, Lorraine S., Reichelt, Stefanie, Ferreira, Manuela, Tavaré, Simon, Inoki, Ken, Shimizu, Shigeomi, Narita, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426290/
https://ncbi.nlm.nih.gov/pubmed/21512002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1205407
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