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Aldehyde dehydrogenase 1A1 expression in breast cancer is associated with stage, triple negativity, and outcome to neoadjuvant chemotherapy

Studies have shown that ALDH1A1 expression in the breast is associated with worse clinical outcome. ALDH1A1 inactivates cyclophosphamide, which is an integral agent in breast cancer chemotherapy regimens. The purposes of this study were to verify these results, to correlate ALDH1A1 expression with c...

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Bibliografiske detaljer
Main Authors: Khoury, Thaer, Ademuyiwa, Foluso O, Chandraseekhar, Rameela, Jabbour, Marah, DeLeo, Albert, Ferrone, Soldano, Wang, Yangyang, Wang, Xinhui
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426278/
https://ncbi.nlm.nih.gov/pubmed/22080062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2011.172
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