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Aldehyde dehydrogenase 1A1 expression in breast cancer is associated with stage, triple negativity, and outcome to neoadjuvant chemotherapy

Studies have shown that ALDH1A1 expression in the breast is associated with worse clinical outcome. ALDH1A1 inactivates cyclophosphamide, which is an integral agent in breast cancer chemotherapy regimens. The purposes of this study were to verify these results, to correlate ALDH1A1 expression with c...

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Detalhes bibliográficos
Main Authors: Khoury, Thaer, Ademuyiwa, Foluso O, Chandraseekhar, Rameela, Jabbour, Marah, DeLeo, Albert, Ferrone, Soldano, Wang, Yangyang, Wang, Xinhui
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426278/
https://ncbi.nlm.nih.gov/pubmed/22080062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2011.172
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