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Modified polynucleotides. I. Investigation of the enzymatic polymerization of 5-alkyl-dUTP-s.

The chemical synthesis of 5-alkyl-dUTP-s and their participation as substrates in poly[d(A-6)] primed polymerization reactions with dATP by E. coli DNA polymerase I enzyme has been described. In comparison with dTTP, at saturating substrate concentrations, the rate of hypochromic effect was found to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sági, J T, Szabolcs, A, Szemzö, A, Otvös, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1977
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC342607/
https://ncbi.nlm.nih.gov/pubmed/333394
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