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Modified polynucleotides. I. Investigation of the enzymatic polymerization of 5-alkyl-dUTP-s.
The chemical synthesis of 5-alkyl-dUTP-s and their participation as substrates in poly[d(A-6)] primed polymerization reactions with dATP by E. coli DNA polymerase I enzyme has been described. In comparison with dTTP, at saturating substrate concentrations, the rate of hypochromic effect was found to...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1977
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC342607/ https://ncbi.nlm.nih.gov/pubmed/333394 |
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