βV-tubulin expression is associated with outcome following taxane-based chemotherapy in non-small cell lung cancer

BACKGROUND: Tubulin-binding agents (TBAs) are effective in non-small cell lung cancer (NSCLC) treatment. Both βIII- and βV-tubulins are expressed by cancer cells and may lead to resistance against TBAs. METHODS: Pre-treatment samples from 65 locally advanced or oligometastatic NSCLC patients, who un...

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Bibliografiske detaljer
Main Authors: Christoph, D C, Kasper, S, Gauler, T C, Loesch, C, Engelhard, M, Theegarten, D, Poettgen, C, Hepp, R, Peglow, A, Loewendick, H, Welter, S, Stamatis, G, Hirsch, F R, Schuler, M, Eberhardt, W E E, Wohlschlaeger, J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Translational Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425975/
https://ncbi.nlm.nih.gov/pubmed/22836512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.324
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