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Coat color determination by miR-137 mediated down-regulation of microphthalmia-associated transcription factor in a mouse model
Coat color is a key economic trait in wool-producing species. Color development and pigmentation are controlled by complex mechanisms in animals. Here, we report the first production of an altered coat color by overexpression of miR-137 in transgenic mice. Transgenic mice overexpressing miR-137 deve...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3425782/ https://ncbi.nlm.nih.gov/pubmed/22847819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.033977.112 |
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