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Crystal structure of a minimal eIF4E–Cup complex reveals a general mechanism of eIF4E regulation in translational repression

Cup is an eIF4E-binding protein (4E-BP) that plays a central role in translational regulation of localized mRNAs during early Drosophila development. In particular, Cup is required for repressing translation of the maternally contributed oskar, nanos, and gurken mRNAs, all of which are essential for...

詳細記述

保存先:
書誌詳細
主要な著者: Kinkelin, Kerstin, Veith, Katharina, Grünwald, Marlene, Bono, Fulvia
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425778/
https://ncbi.nlm.nih.gov/pubmed/22832024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.033639.112
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