Relaxin Signals through a RXFP1-pERK-nNOS-NO-cGMP-Dependent Pathway to Up-Regulate Matrix Metalloproteinases: The Additional Involvement of iNOS

The hormone, relaxin, inhibits aberrant myofibroblast differentiation and collagen deposition by disrupting the TGF-β1/Smad2 axis, via its cognate receptor, Relaxin Family Peptide Receptor 1 (RXFP1), extracellular signal-regulated kinase (ERK)1/2 phosphorylation (pERK) and a neuronal nitric oxide (N...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chow, Bryna Suet Man, Chew, Elaine Guo Yan, Zhao, Chongxin, Bathgate, Ross A. D., Hewitson, Tim D., Samuel, Chrishan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425563/
https://ncbi.nlm.nih.gov/pubmed/22936987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042714
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados