Dengue Virus Serotype 2 Blocks Extracellular Signal-Regulated Kinase and Nuclear Factor-κB Activation to Downregulate Cytokine Production

BACKGROUND: Dengue virus (DENV) infection is the most common mosquito-borne viral disease threatening human health around the world. Type I interferon (IFN) and cytokine production are crucial in the innate immune system. We previously reported that DENV serotype 2 (DENV-2) induced low levels of int...

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Hlavní autoři: Chang, Tsung-Hsien, Chen, Siang-Ru, Yu, Chia-Yi, Lin, You-Sheng, Chen, Yao-Shen, Kubota, Toru, Matsuoka, Mayumi, Lin, Yi-Ling
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425550/
https://ncbi.nlm.nih.gov/pubmed/22927911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041635
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