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Atomistic modeling of protein-DNA interaction specificity: progress and applications

An accurate, predictive understanding of protein-DNA binding specificity is crucial for the successful design and engineering of novel protein-DNA binding complexes. In this review, we summarize recent studies that use atomistic representations of interfaces to predict protein-DNA binding specificit...

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Autors principals: Liu, Limin Angela, Bradley, Philip
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425445/
https://ncbi.nlm.nih.gov/pubmed/22796087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2012.06.002
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