Rapid and Weight-Independent Improvement of Glucose Tolerance Induced by a Peptide Designed to Elicit Apoptosis in Adipose Tissue Endothelium

A peptide designed to induce apoptosis of endothelium in white adipose tissue (WAT) decreases adiposity. The goal of this work is to determine whether targeting of WAT endothelium results in impaired glucose regulation as a result of impaired WAT function. Glucose tolerance tests were performed on d...

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Bibliographic Details
Main Authors: Kim, Dong-Hoon, Sartor, Maureen A., Bain, James R., Sandoval, Darleen, Stevens, Robert D., Medvedovic, Mario, Newgard, Christopher B., Woods, Stephen C., Seeley, Randy J.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2012
Subjects:
Obesity Studies
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425411/
https://ncbi.nlm.nih.gov/pubmed/22733798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1579
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