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Bromocriptine improves glucose tolerance independent of circadian timing, prolactin, or the melanocortin-4 receptor

Bromocriptine, a dopamine D2 receptor agonist originally used for the treatment of hyperprolactinemia, is largely successful in reducing hyperglycemia and improving glucose tolerance in type 2 diabetics. However, the mechanism behind bromocriptine’s effect on glucose intolerance is unclear. Here, we...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Framnes-DeBoer, Sarah N., Bakke, Ellen, Yalamanchili, Suma, Peterson, Hannah, Sandoval, Darleen A., Seeley, Randy J., Arble, Deanna M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985791/
https://ncbi.nlm.nih.gov/pubmed/31794265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00325.2019
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