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Involvement of 5-lipoxygenase activating protein in the amyloidotic phenotype of an Alzheimer’s disease mouse model

BACKGROUND: The 5-lipoxygenase enzyme is widely distributed within the central nervous system and its activity is regulated by the presence and availability of another protein, called 5-lipoxygenase activating protein. While previous works have shown that 5-lipoxygenase is involved in the pathogenes...

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Detalhes bibliográficos
Main Authors: Chu, Jin, Praticò, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425138/
https://ncbi.nlm.nih.gov/pubmed/22697885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-127
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