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The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine
DNA cytosine methylation is a widespread epigenetic mark. Biological effects of DNA methylation are mediated by the proteins that preferentially bind to 5-methylcytosine (5mC) in different sequence contexts. Until now two different structural mechanisms have been established for 5mC recognition in e...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3424535/ https://ncbi.nlm.nih.gov/pubmed/22570415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks332 |
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