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Obese mice exhibit an altered behavioural and inflammatory response to lipopolysaccharide

Obesity is associated with an increase in the prevalence and severity of infections. Genetic animal models of obesity (ob/ob and db/db mice) display altered centrally-mediated sickness behaviour in response to acute inflammatory stimuli such as lipopolysaccharide (LPS). However, the effect of diet-i...

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Bibliographic Details
Main Authors: Lawrence, Catherine B., Brough, David, Knight, Elysse M.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Limited 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424462/
https://ncbi.nlm.nih.gov/pubmed/22328591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009068
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