Exaggerated Increases in Microglia Proliferation, Brain Inflammatory Response and Sickness Behaviour upon Lipopolysaccharide Stimulation in Non-Obese Diabetic Mice

The non-obese diabetic (NOD) mouse, an established model for autoimmune diabetes, shows an exaggerated reaction of pancreas macrophages to inflammatory stimuli. NOD mice also display anxiety when immune-stimulated. Chronic mild brain inflammation and a pro-inflammatory microglial activation is criti...

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Detalhes bibliográficos
Publicado no:Neuroimmunomodulation
Main Authors: McGuiness, Barry, Gibney, Sinead M., Beumer, Wouter, Versnel, Marjan A., Sillaber, Inge, Harkin, Andrew, Drexhage, Hemmo A.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2016
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296925/
https://ncbi.nlm.nih.gov/pubmed/27529430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000446370
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