Comparative Proteomics Reveals a Significant Bias Toward Alternative Protein Isoforms with Conserved Structure and Function

Advances in high-throughput mass spectrometry are making proteomics an increasingly important tool in genome annotation projects. Peptides detected in mass spectrometry experiments can be used to validate gene models and verify the translation of putative coding sequences (CDSs). Here, we have ident...

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Bibliografiska uppgifter
Huvudupphovsmän: Ezkurdia, Iakes, del Pozo, Angela, Frankish, Adam, Rodriguez, Jose Manuel, Harrow, Jennifer, Ashman, Keith, Valencia, Alfonso, Tress, Michael L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424414/
https://ncbi.nlm.nih.gov/pubmed/22446687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mss100
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