Comparative Proteomics Reveals a Significant Bias Toward Alternative Protein Isoforms with Conserved Structure and Function

Advances in high-throughput mass spectrometry are making proteomics an increasingly important tool in genome annotation projects. Peptides detected in mass spectrometry experiments can be used to validate gene models and verify the translation of putative coding sequences (CDSs). Here, we have ident...

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Bibliographische Detailangaben
Hauptverfasser: Ezkurdia, Iakes, del Pozo, Angela, Frankish, Adam, Rodriguez, Jose Manuel, Harrow, Jennifer, Ashman, Keith, Valencia, Alfonso, Tress, Michael L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424414/
https://ncbi.nlm.nih.gov/pubmed/22446687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/mss100
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