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Inhibition of mTOR promotes dendritic cell activation and enhances therapeutic autologous vaccination in mice
Dendritic cells (DCs) are potent inducers of T cell immunity and autologous DC vaccination holds promise for the treatment of cancers and chronic infectious diseases. In practice, however, therapeutic vaccines of this type have had mixed success. Here we show that brief exposure to inhibitors of mec...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3424310/ https://ncbi.nlm.nih.gov/pubmed/22826320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103741 |
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