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CD4(+) T cell dependent IFN-γ production by CD8(+) effector T cells in M. tuberculosis infection

Both CD4(+) and CD8(+) T cells contribute to immunity to tuberculosis, and both can produce the essential effector cytokine IFN-γ. However, the precise role and relative contribution of each cell type to in vivo IFN-γ production are incompletely understood. To identify and quantitate the cells that...

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Detalhes bibliográficos
Main Authors: Bold, Tyler D., Ernst, Joel D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424308/
https://ncbi.nlm.nih.gov/pubmed/22837486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200994
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