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Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes

A major pathway for B cell acquisition of lymph-borne particulate antigens relies on antigen capture by subcapsular sinus macrophages of the lymph node. Here we tested whether this mechanism is also important for humoral immunity to inactivated influenza virus. By multiple approaches, including mult...

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Bibliografiske detaljer
Main Authors: Gonzalez, Santiago F, Lukacs-Kornek, Veronika, Kuligowski, Michael P, Pitcher, Lisa A, Degn, Søren E, Kim, Young-A, Cloninger, Mary J, Martinez-Pomares, Luisa, Gordon, Siamon, Turley, Shannon J, Carroll, Michael C
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424101/
https://ncbi.nlm.nih.gov/pubmed/20305659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1856
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