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Self-antigen presentation by dendritic cells and lymphoid stroma and its implications for autoimmunity

The induction and maintenance of T cell tolerance is essential to prevent autoimmunity. A combination of central and peripheral mechanisms acts to control autoreactive T cells. In secondary lymphoid organs, dendritic cells (DCs) presenting self-antigen were thought to play a major role in the induct...

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Autori principali: Lukacs-Kornek, Veronika, Turley, Shannon J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042528/
https://ncbi.nlm.nih.gov/pubmed/21168318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.11.012
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