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Paired immunoglobulin-like Receptor B (PIR-B) Negatively Regulates Macrophage Activation in Experimental Colitis

BACKGROUND & AIMS: Innate and adaptive immune responses are regulated by crosstalk between activation and inhibitory signals. Dysregulation of the inhibitory signal can lead to aberrant chronic inflammatory diseases such as the inflammatory bowel diseases (IBD). Little is known about negative re...

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Detalhes bibliográficos
Main Authors: Munitz, Ariel, Cole, Eric T., Waddell, Amanda, Groschwitz, Katherine, Ahrens, Richard, Steinbrecher, Kris, Willson, Tara, Han, Xiaonan, Denson, Lee, Rothenberg, Marc E., Hogan, Simon P
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423916/
https://ncbi.nlm.nih.gov/pubmed/20398663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.04.006
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