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History and Pathogenesis of Lynch Syndrome

Lynch syndrome is the familial clustering of colorectal and endometrial cancers. This syndrome is passed in an autosomal dominant fashion within families with defective mismatch repair as the genetic basis for cancer development in these patients. There remains a group of patients who fit clinical d...

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Detalhes bibliográficos
Main Authors: Bansidhar, Brian J., Silinsky, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: Thieme Medical Publishers 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423881/
https://ncbi.nlm.nih.gov/pubmed/23730220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0032-1313776
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