Targeted Deletion of Nrf2 Impairs Lung Development and Oxidant Injury in Neonatal Mice

Aims: Nrf2 is an essential transcription factor for protection against oxidant disorders. However, its role in organ development and neonatal disease has received little attention. Therapeutically administered oxygen has been considered to contribute to bronchopulmonary dysplasia (BPD) in prematurit...

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Bibliographic Details
Main Authors: Cho, Hye-Youn, van Houten, Bennett, Wang, Xuting, Miller-DeGraff, Laura, Fostel, Jennifer, Gladwell, Wesley, Perrow, Ligon, Panduri, Vijayalakshmi, Kobzik, Lester, Yamamoto, Masayuki, Bell, Douglas A., Kleeberger, Steven R.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2012
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Original Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423869/
https://ncbi.nlm.nih.gov/pubmed/22400915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4288
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