Amyloid-β associated clinical decline occurs only in the presence of elevated p-tau

OBJECTIVE: To elucidate the relationship between the two hallmark proteins of Alzheimer's disease (AD), amyloid-β (Aβ) and tau, and clinical decline over time among cognitively normal older individuals. DESIGN: A longitudinal cohort of clinically and cognitively normal older individuals assesse...

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Bibliografiset tiedot
Päätekijät: Desikan, Rahul S., McEvoy, Linda K., Thompson, Wesley K., Holland, Dominic, Brewer, James B., Aisen, Paul S., Sperling, Reisa A., Dale, Anders M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423526/
https://ncbi.nlm.nih.gov/pubmed/22529247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2011.3354
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