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Pharmacologic Agents Elevating cAMP Prevent Arginase II Expression and Proliferation of Pulmonary Artery Smooth Muscle Cells

Arginase II has been shown to be involved in the hypoxia-induced proliferation of human pulmonary artery smooth muscle cells (hPASMCs). The signal transduction pathways responsible for the induction of arginase II are poorly understood. Cyclic AMP is involved in many intracellular processes, and cAM...

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Detalhes bibliográficos
Main Authors: Chen, Bernadette, Calvert, Andrea E., Meng, Xiaomei, Nelin, Leif D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423467/
https://ncbi.nlm.nih.gov/pubmed/22447968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0015OC
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