ING1 and 5-Azacytidine Act Synergistically to Block Breast Cancer Cell Growth

BACKGROUND: Inhibitor of Growth (ING) proteins are epigenetic “readers” that recognize trimethylated lysine 4 of histone H3 (H3K4Me3) and target histone acetyl transferase (HAT) and histone deacetylase (HDAC) complexes to chromatin. METHODS AND PRINCIPAL FINDINGS: Here we asked whether dysregulating...

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Detalhes bibliográficos
Main Authors: Thakur, Satbir, Feng, Xiaolan, Qiao Shi, Zhong, Ganapathy, Amudha, Kumar Mishra, Manoj, Atadja, Peter, Morris, Don, Riabowol, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423394/
https://ncbi.nlm.nih.gov/pubmed/22916295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043671
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