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Beta-Adrenergic Receptor 1 Selective Antagonism Inhibits Norepinephrine-Mediated TNF-Alpha Downregulation in Experimental Liver Cirrhosis

BACKGROUND: Bacterial translocation is a frequent event in cirrhosis leading to an increased inflammatory response. Splanchnic adrenergic system hyperactivation has been related with increased bacterial translocation. We aim at evaluating the interacting mechanism between hepatic norepinephrine and...

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Hlavní autoři: Zapater, Pedro, Gómez-Hurtado, Isabel, Peiró, Gloria, González-Navajas, José Manuel, García, Irma, Giménez, Paula, Moratalla, Alba, Such, José, Francés, Rubén
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423372/
https://ncbi.nlm.nih.gov/pubmed/22916250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043371
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