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Hoxa11 and Hoxd11 Regulate Chondrocyte Differentiation Upstream of Runx2 and Shox2 in Mice

During limb development, posterior Hox genes of the Hoxa- and Hoxd cluster provide positional information along the limb axis. Here we report a new function for Hoxa11 and Hoxd11 in regulating the early steps of chondrocyte differentiation. We analyzed forelimbs of Hoxa11(−/−);d11(−/−) and Ulnaless...

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Bibliografiske detaljer
Main Authors: Gross, Stefanie, Krause, Yvonne, Wuelling, Manuela, Vortkamp, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423364/
https://ncbi.nlm.nih.gov/pubmed/22916278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043553
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