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Protection by glia-conditioned medium in a cell model of Huntington disease
The physiological role of huntingtin and the pathogenic mechanisms that produce the disease are unknown. Mutant huntingtin changes its normal localization and produces cytoplasmic and intranuclear inclusions, changes gene transcription, alters synaptic transmission, impairs mitochondrial activity an...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3423315/ https://ncbi.nlm.nih.gov/pubmed/22919565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/4fbca54a2028b |
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