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Role of neurosteroids in the anticonvulsant activity of midazolam

BACKGROUND AND PURPOSE: Midazolam is a short-acting benzodiazepine that is widely used as an i.v. sedative and anticonvulsant. Besides interacting with the benzodiazepine site associated with GABA(A) receptors, some benzodiazepines act as agonists of translocator protein (18 kDa) (TSPO) to enhance t...

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Autori principali: Dhir, Ashish, Rogawski, Michael A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423249/
https://ncbi.nlm.nih.gov/pubmed/22014182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01733.x
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