Statin therapy lowers muscle sympathetic nerve activity and oxidative stress in patients with heart failure

Despite standard drug therapy, sympathetic nerve activity (SNA) remains high in heart failure (HF) patients making the sympathetic nervous system a primary drug target in the treatment of HF. Studies in rabbits with pacing-induced HF have demonstrated that statins reduce resting SNA, in part, due to...

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Bibliographische Detailangaben
Hauptverfasser: Deo, Shekhar H., Fisher, James P., Vianna, Lauro C., Kim, Areum, Chockalingam, Anand, Zimmerman, Matthew C., Zucker, Irving H., Fadel, Paul J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
Schlagworte:
Integrative Cardiovascular Physiology and Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423160/
https://ncbi.nlm.nih.gov/pubmed/22661508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00289.2012
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