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Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan
Xenobiotic metabolism has been proposed to play a role in modulating the rate of aging. Xenobiotic metabolizing enzymes (XME) are expressed at higher levels in calorically restricted mice (CR) and in GH/IGF-I-deficient, long-lived mutant mice. In this study, we show that many phase I XME genes are s...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Physiological Society
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3423099/ https://ncbi.nlm.nih.gov/pubmed/22693205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00110.2012 |
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