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Novobiocin; an inhibitor of the repair of UV-induced but not X-ray-induced damage in mammalian cells.

In addition to inhibiting replicative DNA synthesis in HeLa cells, novobiocin has a severe effect on the cellular response to UV irradiation, reducing the number of breaks made in pre-existing DNA by the excision repair process. The inhibition of UV repair by novobiocin is reflected in enhanced UV-k...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Collins, A, Johnson, R
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1979
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC342304/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/514814/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/7.5.1311
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