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Novobiocin; an inhibitor of the repair of UV-induced but not X-ray-induced damage in mammalian cells.
In addition to inhibiting replicative DNA synthesis in HeLa cells, novobiocin has a severe effect on the cellular response to UV irradiation, reducing the number of breaks made in pre-existing DNA by the excision repair process. The inhibition of UV repair by novobiocin is reflected in enhanced UV-k...
Guardat en:
| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1979
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| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC342304/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/514814/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/7.5.1311 |
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