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Structural aspects of activation pathways of aspartic protease zymogens and viral 3C protease precursors

The three-dimensional structures of the inactive protein precursors (zymogens) of the serine, cysteine, aspartic, and metalloprotease classes of proteolytic enzymes are known. Comparisons of these structures with those of the mature, active proteases reveal that, in general, the preformed, active co...

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Main Authors: Khan, Amir R., Khazanovich-Bernstein, Nina, Bergmann, Ernst M., James, Michael N. G.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC34228/
https://ncbi.nlm.nih.gov/pubmed/10500110
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