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Structural aspects of activation pathways of aspartic protease zymogens and viral 3C protease precursors

The three-dimensional structures of the inactive protein precursors (zymogens) of the serine, cysteine, aspartic, and metalloprotease classes of proteolytic enzymes are known. Comparisons of these structures with those of the mature, active proteases reveal that, in general, the preformed, active co...

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Bibliographic Details
Main Authors: Khan, Amir R., Khazanovich-Bernstein, Nina, Bergmann, Ernst M., James, Michael N. G.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC34228/
https://ncbi.nlm.nih.gov/pubmed/10500110
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