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The Genetic Basis of Pancreas Cancer Development and Progression: Insights From Whole-Exome and Whole-Genome Sequencing

Pancreatic cancer is caused by inherited and acquired mutations in specific cancer-associated genes. The discovery of the most common genetic alterations in pancreatic cancer has not only provided insight into the fundamental pathways driving the progression from a normal cell, to non-invasive precu...

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Detalhes bibliográficos
Main Authors: Iacobuzio-Donahue, Christine A., Velculescu, Victor E., Wolfgang, Christopher L., Hruban, Ralph H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422771/
https://ncbi.nlm.nih.gov/pubmed/22896692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0315
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