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Development of Therapeutic-Grade Small Interfering RNAs by Chemical Engineering

Recent successes in clinical trials have provided important proof of concept that small interfering RNAs (siRNAs) indeed constitute a new promising class of therapeutics. Although great efforts are still needed to ensure efficient means of delivery in vivo, the siRNA molecule itself has been success...

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Autors principals: Bramsen, Jesper B., Kjems, Jørgen
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422727/
https://ncbi.nlm.nih.gov/pubmed/22934103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00154
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