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Functional and Pharmacological Characteristics of Metabotropic Glutamate Receptors 2/4 Heterodimers

Metabotropic glutamate receptors (mGluRs) were thought until recently to function mainly as stable homodimers, but recent work suggests that heteromerization is possible. Despite the growth in available compounds targeting mGluRs, little is known about the pharmacological profile of mGluR heterodime...

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Bibliographic Details
Main Author: Kammermeier, Paul J.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422699/
https://ncbi.nlm.nih.gov/pubmed/22653971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.078501
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