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Hybrid plasmids containing an active thymidine kinase gene of Herpes simplex virus 1.

The gene for the thymidine kinase (TK) of Herpes simplex virus type 1 (HSV-1) is located in the KpnI m and BamHI p fragments of the genome (Wigler et al., Cell 11, 223-232 (1977)). These fragments have been inserted into the EcoRI and BamHI sites, respectively, of plasmid pBR322, and propagated in E...

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Detalhes bibliográficos
Main Authors: Wilkie, N M, Clements, J B, Boll, W, Mantei, N, Lonsdale, D, Weissmann, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC342267/
https://ncbi.nlm.nih.gov/pubmed/228250
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